c-2. Pathological Evaluation of the Hypophysis Following Pituitary Stalk Section

Sakae FUKUDA
1968 Neurologia medico-chirurgica  
As a series of the studies of the influence of the central nervous system on the various organs, we investigated the ulcer formation when lesions were made at the various parts of the brain, especially the hypothalamus, using about 200' albino rats. In the albino rats, weighing 200-250 grams, electrodes were inserted into the hypothalamic regions and bilateral coagulations were done with the direct current of 2 milliamps for 15 seconds. This procedures produced lesions with 1.5-2.0 mm. in
more » ... .5-2.0 mm. in diameter. The gastric changes were observed every week after making lesion. The gastric changes were classified into the slight, moderate and severe ones. The slight change showed a hyperemia or a single mucosal defect, the moderate change multiple mucosal defects, and the severe change multiple mucosal defects accompanied by an intensive hyperemia and edema. The slight changes appeared in 23.3% of the cases of lesions of the septum" in 25.0% of the cases of the lesions of the preoptic area, in 32.4% of the cases of the lesions of the anterior region, in 15.8% of cases of the lesions of the middle region, and in 28.2% of the cases of the lesions of the posterior hypothalamus. On the other hand, the moderate and severe changes appeared with higher grade in the cases of lesions of the middle and posterior regions than in cases of lesions of the other hypothalamus. c-2. Pathological Evaluation of the Hypophysis Following Pituitary Stalk Section Sakae FUKUDA Department of Neurosurgery, Shizuoka Red Cross Hospital Pituitary stalk section for the palliation of recurrence breast cancer has been -95-
doi:10.2176/nmc.10.95b fatcat:6zjzcow3zvct5kk2fi2vzqr224