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Quantitative Detection of Amino Acids and Carnitine in Human Blood and Quality Control of Peptide Drugs
Journal of Chemistry
In order to deal with the biochemical metabolic disorder and the lack of end metabolites caused by hereditary metabolic diseases, a quantitative detection method of amino acids and carnitine in human blood and the quality control method of polypeptide drugs were proposed. First, a method for the detection of 10 amino acids and 32 acylcarnitine metabolites in human blood was established and analyzed by liquid chromatography tandem mass spectrometry. Through the experimental research on typicaldoi:10.1155/2022/1652592 doaj:e145b6d5e7024ab38cfd82e0f22b95f0 fatcat:pvyel3llqffwdmvliuylm733gm