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Change in lung tumor volume as a biomarker of treatment response: a critical review of the evidence
2010
Annals of Oncology
the evidence indicating that volumetric image analysis of computed tomography scans meets specifications for qualification as a biomarker in clinical trials or the management of individual patients with lung cancer. Methods: Claims of value were broken down into questions about technical feasibility, accuracy, the precision of measurement, sensitivity, the correlations with health outcomes, and the risks of producing misleading information. For each claim, the pertinent literature was reviewed.
doi:10.1093/annonc/mdq051
pmid:20332135
fatcat:ey6kezzlcjgnbj6e4ctp6a3gs4