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The attractiveness of the "bottom-up" approach as a viable route for constructing cell-like systems (Luisi, 2002; Stano, 2019) is clearly evident by the ever increasing number of international projects and initiatives dedicated to this fascinating research (Supplementary Text S1). Such cell-like systems, simply called "synthetic cells" (SCs), "artificial cells" or "protocells" (although with slighly different nuances of meaning) are compartment-based systems (often, but not only, liposomes),doi:10.3389/fmolb.2021.750576 pmid:34540903 pmcid:PMC8446550 fatcat:hxmj6y5smnhaxj6zpctblgxkjy