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Cells around epithelial wounds must first become aware of the wound in order to initiate the wound healing process. An initial response to an epithelial wound is an increase in cytosolic calcium followed by complex calcium signaling events. While these calcium signals are driven by both physical and chemical wound responses, cells around the wound will all be equipped with the same cellular components to produce and interact with the calcium signals. Here, we have developed a mathematical modeldoi:10.1101/2022.08.24.505161 fatcat:5eygk3vuqvaurgqhsvbwknavtm