& Objectives: Cardiovascular diseases are usually associated with high rates of mortality, lack of self-reliance, and depression in the patients. Cardiac rehabilitation program is a well-established program causing to relieve depression. The purpose of this study was to determine the effects of cardiac rehabilitation programs on depression control in patients who had undergone Coronary Percutaneous Intervention (PCI). Methods: This clinical trial study was performed on 100 patients selected by

more »

... onvenience sampling method after undergoing PCI. Data were collected using "demographic information survey" and "Beck Depression Inventory" questionnaires before and after rehabilitation (2 and 10 weeks after angioplasty in control group and 2 weeks after angioplasty and after 8 weeks of rehabilitation course in case group). Data analysis was done in SPSS version 18 and by student's t test, pair t test, chi-square at significant level of p<0.05. Results: Out of 100 patients, respective mean ages were 57.46±8.06 and 60.64±10.62 year for case and control groups and 60% was male. There was a significant relationship between depression scores in before and after cardiac rehabilitation in the cases (p<0.001). However, correlation between depression scores after 2 and 10 weeks of angioplasty was not significant (p=0.054). There was also prominent differences in depression scores between case and control groups (p<0.001). Conclusion: These findings suggest that cardiac rehabilitation may be an effective intervention for depression relieve after PCI.