In order to evaluate the effects of seed priming on morpho-physiological traits of winter wheat under drought stress, an experiment was conducted under semi-controlled conditions in the city of Ooshnaviyeh of Iran, during 2011-2012. This Study was carried out Factorial experiment based on RCBD design with 3 replications to determine the influence of Irrigation (normal and drought stress) and Priming control (with no priming), Ascrobat and hardening. Analysis of variance showed effect of

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... on on all characters except for 1000-grain weight and priming effect for all traits studied was significant. Also the interaction between priming and irrigation effects on Photosynthesis, Peduncle length, number grain per spike, number spike/m -2 was statistically significant. In this research drought significantly reduced all traits, as drought stress reduced grain yield 7.16% in comparison with control. Furthermore priming with Ascrobat increased plant height, photosynthesis, number spikelet per spike, 1000-grain weight (TKW) and grain yield in comparison with other treatments so that the priming with Ascrobat increased grain yield by 9% compared with control. Finally with regard to the compare mean of interaction between treatments it can be concluded, seed priming with Ascrobat modified the effect of drought stress.