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A simple and efficient method has been developed for conversion of arenecarbaldehyde-3-methylquinoxalin-2-ylhydrazones to 3-(2-methylquinoxalin-3-yl)-2-(substitutedphenyl)thiazolidin-4-ones in good yields using microwave irradiation technique on silica as solid support under solvent free conditions. The synthesized compounds were characterized by elemental microanalysis, infrared spectroscopy, 1 H NMR, and mass spectroscopy. All the synthesized thiazolidinones were investigated for theirdoi:10.5012/bkcs.2010.31.5.1219 fatcat:nwukb7cd7rf5zodyfdmlmsoshq