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The small and large ribosomal subunits depend on each other for stability and accumulation
[article]
2018
bioRxiv
pre-print
The 1:1 balance between the numbers of large and small ribosomal subunits can be disturbed by mutations that inhibit the assembly of one of the subunits. We have investigated if the cell has mechanisms to counteract an imbalance of subunits. We show that accumulation of 40S subunits stops after abrogating 60S assembly. In contrast, cessation of the 40S pathways does not prevent 60S accumulation, but does, however, lead to fragmentation of the 25S rRNA in 60S subunits. Even though 40S subunits
doi:10.1101/384362
fatcat:yecg2cpbr5hdzlo3txqadmdenu