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The hippocampus expresses a large number of androgen receptors; therefore, in men it is potentially vulnerable to the gradual age-related decline of testosterone levels. In the present study we sought to elucidate the nature of the relationship between testosterone and hippocampal volume in a sample of middle-aged male twins (average age 55.8 years). We found no evidence for a correlation between testosterone level and hippocampal volume, as well as no indication of shared genetic influences.doi:10.1016/j.neuroimage.2011.09.044 pmid:21983185 pmcid:PMC3230702 fatcat:rwjrzsqrlfgvdnbbk6chtiqz5m