Objective To analyze the factors associated with additional surgery after endoscopic resection of colorectal lesions. Methods Seventy-seven cases of colorectal lesions treated with endoscopic resection and additional surgery in General Hospital of Northern Theater Command from January 2012 to December 2017 were included in this study. According to the pathological changes, lymph node hyperplasia or vascular invasion, these patients were divided into positive group (n=13) and negative group

more »

... ). The general condition, lesion characteristics, complete resection rate and lifting sign were compared between the two groups. Univariate and multivariate logistic regression analyses were performed for risk factors for additional surgery. Results There were no significant differences in the general condition, lesion characteristics, and endoscopic adverse events between the two groups. Compared with the negative group, the rate of resection of the lesion in the positive group was significantly reduced (χ2=17.936, P<0.001), and the proportion of poor elevation significantly increased (χ2=28.643, P<0.001). Logistics univariate analysis showed that en bloc resection (OR=0.08, 95%CI 0.02-0.34, P<0.001), as a protective factor, led to a decrease in risk of positive results; while the inadequate lifting sign (OR=13.78, 95%CI 4.32-43.97, P<0.001), as a risk factor, led to an increase in risk of positive results. Logistics multivariate analysis also showed that the en bloc resection (OR=0.13, 95%CI 0.08- 0.31, P<0.001) could reduce the risk of positive results and was an independent protective factor; while the inadequate lifting sign (OR=10.62, 95%CI 4.59-31.71, P<0.001) increased the risk of positive results, which was a risk factor. Conclusions Surgery is recommended for endoscopic treatment of postoperative cases with poorly lifting and multiple resections. DOI: 10.11855/j.issn.0577-7402.2019.07.15