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Developmental origins and lineage descendants of endogenous adult cardiac progenitor cells
2014
Stem Cell Research
Preserved Fulltext
Mammalian hearts carry a number of primitive stem cell-like populations, although the magnitude of their contribution to tissue homeostasis and repair remains controversial. Recent CRE recombinase-based lineage tracing experiments suggest only a minor contribution to the formation of new cardiomyocytes from such cells, albeit one that might be augmented therapeutically. As the field explores clinical translation of cardiac stem cells, it will be important to understand the biology of these
doi:10.1016/j.scr.2014.09.008
pmid:25459343
fatcat:ejnuvdf6nfgsrouuuysqekck3e