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Molecular Subgroups of Endometrial Carcinoma in Romanian Patients
2020
Revista de chimie (Bucuresti)
Molecular classification of endometrial carcinoma (EC) has represented a breakthrough ever since the TCGA (The Cancer Genome Atlas) project published it in 2013. Four distinct molecular subgroups were recognized based on somatic copy number alterations and tumor mutational burden: POLE (polymerase-epsilon) ultramutated, MSI (microsatellite instability) hypermutated (MSI-H), copy number low (CNL) and copy number high (CNH). However, implementing a standardized algorithm in current practice is
doi:10.37358/rc.20.9.8337
fatcat:o3q2yzz37jdzvovn7x6d2ktqa4