96-47: Retrospective Analysis of Patients with Chagas Heart Disease and Implantable Cardioverter Defibrillator

Abud Atilio, Carlessi Adrian, Tomas Leandro, Arceluz Martin, Goyeneche Raul, Folonier David, Fernandez Ricardo
2016 Europace  
The goal of the study was to analyze the evolution of chagásic patients in whom automatic implantable cardioverter defibrillator (ICD) was implanted as secondary prevention for sudden cardiac death, and to evaluate the relationship between the different selected variables with overall mortality (OM) and readmissions by heart failure (HF). Material and Methods: There were 37 patients included with Chagas heart disease in whom ICD was implanted as secondary prevention for sudden cardiac death
more » ... coronary angiography that showed absence of coronary artery disease. The average follow-up was 72 months. Results: At the time of implantation, 49.1% were males and the average age of the population was 55 years. Average EF was 41%. Fifty three percent of patients presented intraventricular conduction disorder (IVCD), 35% CRBBB and 18% CLBBB. In 75.7% of patients electrical therapy was applied, 26 (70.2%) received antitachycardia pacing, and 25 (68.6%) received appropriate shocks. The average time interval between the implantation of the device and the first appropriate electrical therapy was 178.6 days. In 19 patients (51.9%) electrical storms were observed. The average of ventricular pacing was 29.3% Mortality was 26% (3.25% yearly) and readmissions by HF occurred in 7 patients (18.9%). In univariate analysis, EF ,40% ( p ¼ 0.05), IVCD ( p ¼ 0.05), electrical storm ( p ¼ 0.025), appropriate shock ( p ¼ 0.045) and ventricular pacing percentage (VPP) greater than 40% ( p ¼ 0.004), were the variables associated to overall mortality, with IVCD persisting as the single independent predictor in multivariate analysis. In univariate analysis, the parameters predicting readmission by HF were: EF ,40% ( p ¼ 0.002) and VPP greater than 40% ( p ¼ 0.018) and in multivariate analysis only EF ,40%. Conclusion: The EF , 40%, IVCD, the presence of electrical storms and VPP greater than 40% were the variables significantly associated to OM; while EF ,40% and VPP greater than 40% were the variables significantly associated to readmissions by HF.
doi:10.1093/europace/18.suppl_1.i73 fatcat:i4gzm42cnzgibp27vubhw3sgra