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PET Molecular Imaging Research of Levodopa-Induced Dyskinesias in Parkinson's Disease
2017
Current Neurology and Neuroscience Reports
Purpose of Review To review the current status of positron emission tomography (PET) molecular imaging research of levodopa-induced dyskinesias (LIDs) in Parkinson's disease (PD). Recent Findings Recent PET studies have provided robust evidence that LIDs in PD are associated with elevated and fluctuating striatal dopamine synaptic levels, which is a consequence of the imbalance between dopaminergic and serotonergic terminals, with the latter playing a key role in mishandling presynaptic
doi:10.1007/s11910-017-0794-2
pmid:28975571
pmcid:PMC5626800
fatcat:vogy2ji6u5eg7fb3mldso57zme