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Emerging Corynebacterium glutamicum systems biology
2006
Journal of Biotechnology
Corynebacterium glutamicum is widely used for the biotechnological production of amino acids. Amino acid producing strains have been improved classically by mutagenesis and screening as well as in a rational manner using recombinant DNA technology. Metabolic flux analysis may be viewed as the first systems approach to C. glutamicum physiology since it combines isotope labeling data with metabolic network models of the biosynthetic and central metabolic pathways. However, only the complete
doi:10.1016/j.jbiotec.2005.12.002
pmid:16406159
fatcat:w6f2mvgatjgjdjlvnegm2suqyy