Identifying the molecular basis of functions in the transcriptome of the social amoeba Dictyostelium discoideum

T.J. Whitney, D.G. Gardner, M.L. Mott, M. Brandon
2010 Genetics and Molecular Research  
Dictyostelium discoideum transcriptome vides relative expression levels, which allows us to rank order the expressed genes. We found that a large number of ribosomal proteins were expressed at high levels, while various components of the proteosome were expressed at low levels. The only identifiable transmembrane signaling system components expressed in amoebae are related to quorum sensing, and their expression levels were relatively low. The most highly expressed gene in the amoeba
more » ... me, dutA untranslated RNA, is a molecule with unknown function that may serve as an inhibitor of translation. These results suggest that high-density amoebae have not initiated development, and they also suggest a mechanism by which the transition into the development program is controlled.
doi:10.4238/vol9-1gmr752 pmid:20309825 fatcat:vnamih6zgra7pf24afw4bzcwxy