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Bone models set for studying apatite mineralization tend to use excess of organic additives and a very low concentration of collagen in the light of those described in the biological tissue. However, the activity of soluble additives during mineral deposition is highly dependent on their concentration and confinement state, among others. Here, we investigate the role of concentration of organic additives described as key components in bone mineralization, i.e. the bioinspired syntheticdoi:10.1021/acs.cgd.1c00316.s001 fatcat:ofi676eh7vacjgfkekribcrmeu