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Twelve pacients admitted to the Hospital Calvo Mackenna with diagnosis Tuberculosis of the first Trimester of life-are studied. Clinical, laboratory and patological findings are described. Features used to the diagnosis of congenital Tuberculosis are analized. Based upon those, live cases are considered as connatal Tuberculosis. Tuberculosis of the first trimester of life is a patological entity that still shows diagnostic diticulties and a high incidence of mortality, so it must be kept indoi:10.4067/s0370-41061981000100003 fatcat:ejrtk5robncyvazr36xzwgkv3m