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Stem Cell Reports
In vitro surrogate models of human cardiac tissue hold great promise in disease modeling, cardiotoxicity testing, and future applications in regenerative medicine. However, the generation of engineered human cardiac constructs with tissue-like functionality is currently thwarted by difficulties in achieving efficient maturation at the cellular and/or tissular level. Here, we report on the design and implementation of a platform for the production of engineered cardiac macrotissues from humandoi:10.1016/j.stemcr.2019.05.024 pmid:31231023 pmcid:PMC6626888 fatcat:b5hmzvroh5ez5fe27abdl5eo2y