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Wolbachia infections are a fascinating example of reproductive parasitism with strong potential to combat vector-borne diseases, due to their combined ability to spread in insect populations and block pathogen replication. Though the Wolbachia factors mediating the notable reproductive manipulation cytoplasmic incompatibility (CI) have now been identified as prophage WO genes cifA and cifB, the relative role of these genes is still intensely debated, with different models claiming that CIdoi:10.1101/2021.04.20.440637 fatcat:lwc2d6x3yvgnzfpuhh2j3tacwm