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Motivation: Many genomes have been completely sequenced. However, detecting and analyzing their proteinprotein interactions by experimental methods such as coimmunoprecipitation, tandem affinity purification, and Y2H is not as fast as genome sequencing. Therefore, a computational prediction method based on the known protein structural interactions will be useful to analyze large-scale protein-protein interaction rules within and among complete genomes. Results: We confirmed that all thedoi:10.1093/bioinformatics/bti512 pmid:15914543 fatcat:nrsvweppdvgxjidkixxitemgeq