Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione-depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats

Suzanne Geenen, James W. T. Yates, J. Gerry Kenna, Frederic Y. Bois, Ian D. Wilson, Hans V. Westerhoff
2013 Integrative Biology  
Model equations: 1 + 14.2722 · [bmet] · [para] 1000 (0.67994 + [bmet]) · (20. + [para] 1000 ) Electronic Supplementary Material (ESI) for Integrative Biology This journal is
doi:10.1039/c3ib20245c pmid:23632663 fatcat:5llmnvbf2zb2lmpfj2xn6ifdsm