Four-dimensional twisted group lattices are used as models for space-time structure. Compared to other attempts at space-time deformation, they have two main advantages: They have a physical interpretation and there is no difficulty in putting field theories on these structures. We present and discuss ordinary and gauge theories on twisted group lattices. We solve the free field theory case by finding all the irreducible representations. The non-abelian gauge theory on the two-dimensional

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... d group lattice is also solved. On twisted group lattices, continuous space-time translational and rotational symmetries are replaced by discrete counterparts. We discuss these symmetries in detail. Four-dimensional twisted group lattices can also be used as models for non-trivial discrete compactifactions of certain ten-dimensional spaces.