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Disseminated and circulating tumour cells and their role in breast cancer
Folia biologica (Praha)
Metastatic spread of the primary tumour is responsible for the vast majority of cancer-related deaths. Detection of disseminated tumour cells in the bone marrow and circulating tumour cells in the peripheral blood is correlated with early metastatic relapse in breast cancer. Positive detection of disseminated tumour cells was associated with poor overall survival of patients. Current research has been focused on integrating minimal residual disease as a prognostic and predictive tool in thepmid:22849858 fatcat:i7jmj5jnezhibawnbdd4rt3fly