Neuropsychological and interpersonal antecedents of youth depression

Megan Flynn, Karen D. Rudolph
2010 Cognition & Emotion  
This research examined neuropsychological and interpersonal factors that jointly confer vulnerability to youth depression. We proposed that (1) a reduced posterior right hemisphere bias during the processing of facial expressions contributes to subsequent depressive symptoms in youth, and (2) maladaptive responses to interpersonal stress account for this association. Drawing from theory and research indicating sex differences in rates of hemispheric development, we also investigated sex
more » ... ces in the associations among a reduced posterior right hemisphere bias, maladaptive responses to interpersonal stress, and depressive symptoms. Hypotheses were examined in a longitudinal study of 95 4 th -8 th graders (M age = 12.33, SD = 1.10). Results supported the notion that a reduced posterior right hemisphere bias confers vulnerability to depressive symptoms over time in a sex-specific fashion, and implicate maladaptive stress responses as an explanatory mechanism. Psychobiological theory and research suggest that atypical patterns of regional brain activity, including irregularities in both anterior and posterior regions, play a role in
doi:10.1080/02699930802584417 pmid:26273121 pmcid:PMC4532390 fatcat:qckscyyyfnc7xk3gcbnpidtmr4