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Requirement of splicing factor hnRNP A2B1 of hnRNPs for tumorigenesis of melanoma stem cells
[post]
2020
unpublished
Background: Cancer stem cells play essential roles in tumorigenesis, thus being the important targets for tumor therapy. The hnRNP family proteins, the important splicing factors, are found to be associated with tumor progression. However, the influence of hnRNPs on cancer stem cells has not been extensively explored.Methods: Quantitative real-time PCR and Western blot were used to examine the gene expression level. RNA immunoprecipitation assay and RNA sequencing were conducted to identify the
doi:10.21203/rs.3.rs-92870/v1
fatcat:utcsptaxwzh4ppzo5nigpfe3me