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Programmable modification of cell adhesion and zeta potential in silica microchips
Lab on a Chip
Spatial patterning of thin polyacrylamide films bonded to self-assembled monolayers on silica microchannels is described as a means for manipulating cell-adhesion and electroosmotic properties in microchips. Streaming potential measurements indicate that the zeta potential is reduced by at least two orders of magnitude at biological pH, and the adhesion of several kinds of cells is reduced by 80-100%. Results are shown for cover slides and in wet-etched silica microchannels. Because thedoi:10.1039/b210621n pmid:15100798 fatcat:dknbw5xb7fbjrbkz2eidhed4ly