The concept of bilateral simultaneous occlusion and ideal distribution of the occlusal force are important component of the optimum occlusal condition. The Down syndrome (DS) children have many orofacial dysfunction and developmental deficiency which affect the harmony between the stomatognathic systems among these children. This paper reviews the clinical features of DS, occlusion development, mastication, bite force, factors affecting them, and methods of occlusal analysis. Copyright©2017,

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... aa S Albusaily et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.