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Epithelial–Mesenchymal Transition Participates in the Formation of Vestibular Flat Epithelium
2021
Frontiers in Molecular Neuroscience
The vestibular sensory epithelium of humans and mice may degenerate into a layer of flat cells, known as flat epithelium (FE), after a severe lesion. However, the pathogenesis of vestibular FE remains unclear. To determine whether the epithelial–mesenchymal transition (EMT) participates in the formation of vestibular FE, we used a well-established mouse model in which FE was induced in the utricle by an injection of streptomycin into the inner ear. The mesenchymal and epithelial cell markers
doi:10.3389/fnmol.2021.809878
pmid:34975404
pmcid:PMC8719593
fatcat:6e6ps5xmqbelvowngmcvtkekjm