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Erythropoietin and Its Receptor in Breast Cancer: Correlation with Steroid Receptors and Outcome
Cancer Epidemiology, Biomarkers and Prevention
Autocrine/paracrine erythropoietin (EPO) action, promoting cell survival and mediated by its receptor (EPOR) in various solid tumors, including breast carcinoma, questions about the prognostic and therapeutic interest of this system. The expression of EPO/EPOR is steroid dependent in some tissues; however, a clear relationship of EPO/EPOR and steroid receptors in breast cancer has not been established thus far. Recently, the field of steroid receptors has expanded, including rapid effectsdoi:10.1158/1055-9965.epi-06-1023 pmid:17932349 fatcat:sra6knckdveixpmphotun2ew3q