It has been reported that frequency analysis results (MF: mean frequency, etc.) of spontaneous magnetoencephalographic(MEG) activity are useful as one of the indexes for diagnosing brain functions such as dementia. It is important that the same diagnosis results be obtained when the same subject is examined at another site or on another day. However, the results are easily changed by interference signals. Therefore, in this study, we applied the DSSP(Dual Signal Subspace Projection) method to

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... e spontaneous brain activity data recorded under a variety of conditions with MEG, and investigated its effect. MF value was improved by performing DSSP on the data containing the interference signal. It was confirmed that even if DSSP was applied to clean data, there was almost no change in the MF value compared to the case without DSSP, and the frequency spectrum of the alpha-wave band did not change. It was suggested that the drawback of applying DSSP are extremely small.