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Electron cryomicroscopy as a powerful tool in biomedical research
2018
Journal of Molecular Medicine
A human cell is a precisely regulated system that relies on the complex interaction of molecules. Structural insights into the cellular machinery at the atomic level allow us to understand the underlying regulatory mechanism and provide us with a roadmap for the development of novel drugs to fight diseases. Facilitated by recent technological breakthroughs, the Nobel prize-winning technique electron cryomicroscopy (cryo-EM) has become a versatile and extremely powerful tool to solve routinely
doi:10.1007/s00109-018-1640-y
pmid:29730699
pmcid:PMC5988769
fatcat:tzmleiw7ufcpbkyhor4bf3b5ci