For most of the last decade, the field of growth disorders has evolved with more decisive signs of its detrimental potential to the health and development of fetuses, neonates, childhoods, and adults. This introductory chapter is, briefly, embracing themes on the growth disorders including growth hormone deficiency (GHD) and fetal growth restriction (intrauterine growth restriction (IUGR)). It then goes on to cover the effects of GHD or IUGR on different biological systems. References [1]

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... o D, Díaz O, Devesa P, Devesa J. Growth hormone (GH) and cardiovascular system. International Journal of Molecular Sciences. 2018;19:pii. E290 [2] Devesa J, Almengló C, Devesa P. Multiple effects of growth hormone in the body: Is it really the hormone for growth? Clinical Medicine Insights: Endocrinology and Diabetes. 2016;9:47-71 [3] Laron Z, Galatzer A. Growth hormone, somatomedin and prolactin-Relationship to brain function. Brain & Development. 1985;7:559-567 [4] Lobie PE, Garcia-Aragon J, Lincoln DT, Barnard R, Wilcox JN, Waters MJ. Localization and ontogeny of growth hormone receptor gene expression in the central nervous system. Brain Research. Developmental Brain Research. 1993;74:225-233 [5] Mateus J, Newman RB, Zhang C, Pugh SJ, Grewal J, Kim S, et al. Fetal growth patterns in pregnancy-associated hypertensive disorders: NICHD Fetal Growth Studies. American Journal of Obstetrics and Gynecology. 2019;221:635.e1-635.e16 Growth Disorders and Acromegaly 4 Growth Disorders and Acromegaly 6