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Sexual dysfunctions such as diminished libido, erectile dysfunction, arousal problems, or delayed orgasm are common side effects of antidepressant medication. However, spontaneous ejaculation is a rare side effect caused by antidepressants. Several case of spontaneous ejaculation have been reported about escitalopram, venlafaxine and reboxetine in the literature. In this paper, a 46-year-old man who developed spontaneous ejaculation with duloxetine is discussed. Duloksetine bağlı gelişendoi:10.5455/apd.189811 fatcat:hqpmw3uydbcs3jkl2cfwytrb3a