HIV-Associated Anal Cancer

Mark Bower, Tom Powles, Tom Newsom-Davis, Christina Thirlwell, Justin Stebbing, Sundihya Mandalia, Mark Nelson, Brian Gazzard
2004 Journal of Acquired Immune Deficiency Syndromes  
HIV-associated anal carcinoma, a non-AIDS-defining cancer, is a human papillomavirus-associated malignancy with a spectrum of preinvasive changes. The standardized incidence ratio for anal cancer in patients with HIV/AIDS is 20-50. Algorithms for anal cancer screening include anal cytology followed by high-resolution anoscopy for those with abnormal findings. Outpatient topical treatments for anal intraepithelial neoplasia include infrared coagulation therapy, trichloroacetic acid, and
more » ... acid, and imiquimod. The development of cost-effective national screening programs for HIV-associated anal cancer remains a challenge.
doi:10.1097/00126334-200412150-00004 pmid:15577408 fatcat:azqvmx5wc5hvhlyxqjehjrchjm