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The Cumulative Influence of Hyperoxia and Hypercapnia on Blood Oxygenation and R2*
2015
Journal of Cerebral Blood Flow and Metabolism
Cerebrovascular reactivity (CVR)-weighted blood-oxygenation-level-dependent magnetic resonance imaging (BOLD-MRI) experiments are frequently used in conjunction with hyperoxia. Owing to complex interactions between hyperoxia and hypercapnia, quantitative effects of these gas mixtures on BOLD responses, blood and tissue R Ã 2 , and blood oxygenation are incompletely understood. Here we performed BOLD imaging (3 T; TE/TR = 35/2,000 ms; spatial resolution = 3 × 3 × 3.5 mm 3 ) in healthy volunteers
doi:10.1038/jcbfm.2015.168
pmid:26174329
pmcid:PMC4671125
fatcat:26rfy5n24bbezngo7ak3qj66ta