1920 Journal of the American Medical Association  
This case will be of interest on account of the unusually rare type of protein hypersensitization causing anaphylactic bronchial spasm. It also emphasizes the importance of careful history taking, with the view of searching for a possible clue in the etiology of the existing bronchial asthma. REPORT OF CASE J. M., a white man, aged 29, pharmacist for the last six years, referred by Dr. Robert Kahn, New York, twelve years before contracted an acute bronchitis, which persisted throughout the
more » ... throughout the winter and early spring. With the return of the cold weather each year, he would be again subjected to the bronchitic symptoms of previous winters, consisting of occasional wheezing, dry cough and slight dyspnea, with intervals of relief from one to seven days. In the fall of 1919, bronchitis set in as usual. In December, the patient first complained of much running of the nose, followed by an irritating and distressing dry cough, and respiratory oppression. Soon after, he experienced for the first time a typical bronchial spasm. These symptoms would come on when he was working in the drug store, and especially when compound¬ ing powders. Past and family histories were negative. Previous to coming under my observation, several nose and throat and general physical examinations were conducted by various specialists, who found him to be of excellent physique,
doi:10.1001/jama.1920.02620430029008 fatcat:lzg7bdu6arapdbevv237lruclm