Diagnosing and Managing Androgen Insensitivity Syndrome

Kimassoum Rimtebaye, Edouard Hervé Moby Mpah, Cyril Kamadjou, Arya Zarif Agah Tashkand, Franklin Danki Sillong, Mignagnal Kaboro, Lamine Niang, Serigne Magueye Gueye
2017 Open Journal of Urology  
Androgen insensitivity syndrome is a rare congenital abnormality of genital organs revealing a female phenotype in a person with XY chromosomes. The aim of our work is to describe the clinical aspects, to determine the chromosomal sex and to report our therapeutic management. Observation: A 28-year-old woman with female phenotype, feminine voice, normal breast development, normal underarms and pubic hair, absence of menstruation, fusion of small and large vaginal lips leaving a small pertuis to
more » ... a small pertuis to serve as urethral meatus. On the dorsal surface of the large, left lip was a mass the size of a date. Hormonal balance was normal. A feminizing genitoplasty was performed as well as excision of the mass. Histological analysis of the mass concluded that it was a feminizing testicular. Conclusion: Androgen insensitivity syndrome is a rare abnormality of the genitals. Multidisciplinary management is essential both for the designation of the breeding sex and feminizing genitoplasty.
doi:10.4236/oju.2017.711026 fatcat:yd6detcqcnaehmoeo4bdikyg5i