The long-term outcome of 327 patients with cerebrovascular disease (CVD) admitted to the Department of Neurology, National Sendai Hospital, during the period from 1979 to 1989 was analyzed. The follow-up rate was 99.7%, and the mean follow-up period was 60.5 months (one to 150 months). The activities of daily living (ADL) grade with CVD at discharge was 34% of patients with CVD for the excellent group, 32% for the good group, 14% for the fair group, 10% for the poor group and 9% for the dead

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... up. The ADL grade at follow-up was 30%, 21%, 13%, 8% and 28%, respectively, for the five groups. The ADL grade worsened significantly with age at both discharge and follow-up. The survival curve depended on the age at onset of CVD. The older the age at onset and the poorer the ADL grade at discharge, the shorter the mean survival period. In the poor group for ADL at discharge, the mean survival period was 75.3 months for patients under age 60 at onset, 61.8 months for patients aged 60 to 74 years at onset and 22.7 months for patients aged 75 or older at onset. The cause of death was the CVD itself in 66% of the CVD patients, Recurrent attacks were rather frequent in the first two years after the onset of CVD. The mean annual recurrence rate, was calculated to be 4.2% for the 12-year follow-up period.