Dendritic compound of triphenylene-2,6,10-trione ketal-tri-{2,2-di-[(N-methyl-N-(4-pyridinyl) amino) methyl]-1,3-propanediol}: an easily recyclable catalyst for Morita-Baylis-Hillman reactions

Rong-Bao Wei, Hong-Lin Li, Ya Liang, Yan-Ru Zang
2009 Journal of Biomedical Science and Engineering  
A novel Dendritic Compound (2) of triphenylene-2,6,10-trione ketal-tri-{2,2-di-[(N-methyl-N-(4-pyridinyl) amino)methyl]-1,3-propanediol} was conveniently synthesized by aromatization of cyclohexanedione mono-ketal, ketal-exchange reaction with 2,2-dibromomethyl-1,3-propanediol and nuclophilic substitution with N-methylaminopyridine as nuclophilic reagent. The Morita-Baylis-Hillman reaction of various aryl aldehydes with methyl vinyl ketone and acrylonitrile in (DMF/cyclohexane, 1/1, v/v) has
more » ... n investigated by using Dendritic Compound (2) as catalyst. The corresponding Morita-Baylis-Hillman adducts was obtained in good yields by using the recycled and reactivated dendritic catalyst.
doi:10.4236/jbise.2009.25047 fatcat:j7xbmth34veqjh37q5fdib6wti