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HIV-AIDS is one of the biggest challenges of the 21st century to cure. However, in the current scenario, various antiretroviral drugs are available which makes the condition chronic rather than worse which manages to increase the survival rate. Antiretroviral drugs are manageable but the bioavailability, lower permeability; poor half-life of the drug limits the potent activity. High dose drug administration leads to higher toxicity which arrays adverse effects and develops resistance againstdoi:10.31782/ijcrr.2020.121910 fatcat:ik2kxcl5ezg55cxqrwhgaapyze