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system presents the colloid reactions concerned with the distribution of water in normal and diseased tissues. Fischer's theory of edema is discussed fully. There follows a similar discussion of salt distribution, assimilation and dissimilation \p=m-\processesinvolving the conversion of crystalloid foodstuff into colloids which may be retained for use. Growth, the formation of layered structures, ossification, and certain pathologic changes are given a colloidal chemical basis. The colloidaldoi:10.1001/jama.1919.02610360054033 fatcat:m7l6yugagjdmretrmpkx4f7dre