Carotid Sinus as a Mechanotransducer of Shear Oscillation [post]

2019 unpublished
Objective The carotid sinus is a region in the cardiovascular system where ow characteristics are transduced by the autonomic nervous apparatus to help maintain cardiovascular homeostasis. The objective of this study is therefore to determine whether the carotid sinus acts as a mechanotransducer of wall shear stress oscillation. Results By utilizing magnetic resonance angiograms of undiseased carotid bifurcations, computational uid dynamic simulations of blood ow were constructed. Employing
more » ... cted. Employing boundary conditions meant to emulate normal blood ow at rest, the oscillatory shear index (OSI) was tabulated and mapped. The areas of highest OSI were well-isolated in the regions of the carotid bifurcations generally considered to comprise the carotid sinus.
doi:10.21203/rs.2.11025/v1 fatcat:4yvbxbbkvvag7kwlhcc4cc7ufq