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CD56 + cells in canine blood leukocytes were characterized by flow-cytometric analysis of peripheral blood of 30 healthy adult beagle-dogs (15 males and 15 non-pregnant females). In 19 of the 30 dogs, anti human CD56 antibody, Leu-19, reacted with 8.8-21.7% of peripheral blood lymphocytes. All CD56 + cells simultaneously expressed CD3 molecules on their surface. Further phenotypic analysis revealed that 50.6 ± 13.1% of the CD56 + cells showed CD4 -CD8 + phenotype and 43.7 ± 10.1% showed CD4 +doi:10.1292/jvms.64.441 pmid:12069078 fatcat:txje6d2kfvemjjmed7vyuzhvk4