Objective To investigate the effect of Duraphat in the prevention of dental caries of abutment teeth in removable partial denture. Methods 100 patients who suffered from dentition defect were recruited. We used self-control methods.Abutment teeth of one side were randomly assigned to control group, abutment teeth of another side were assigned to experimental group. In experimental group, Duraphat was applied every six months. The prevalence of caries of abutment teeth of removable partial

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... e was recorded 3 years later. Results The data showed that the caries prevalence of experimental side was significantly lower than the control side (P<0.01). Conclusion It is a simple and effective way to prevent caries in the abutment teeth of removable partial denture with Duraphat.