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An Update on Silent Corticotroph Adenomas: Diagnosis, Mechanisms, Clinical Features, and Management
2021
Cancers
With the introduction of 2017 World Health Organization (WHO) classification of endocrine tumors, T-PIT can serve as a complementary tool for identification of silent corticotroph adenomas (SCAs) in some cases if the tumor is not classifiable by pituitary hormone expression in pathological tissue samples. An increase of the proportion of SCAs among the non-functioning pituitary adenomas (NFPAs) has been witnessed under the new rule with the detection of T-PIT-positive ACTH-negative SCAs.
doi:10.3390/cancers13236134
pmid:34885244
fatcat:kx7wnddsirapfp5b2otdgpajqa