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Catecholamines inhibit steroidogenesis by cultured porcine thecal cells
1990
FEBS Letters
The ovaries of many species contain catecholamines and /&adrenergic receptors. The present studies were done to determine if catecholamines play a role in the regulation of androgen production by porcine theta cells. Basal and luteinizing hormone (LH)-stimulated androstenedione production was significantly inhibited by noradrenaline and isoproterenol, The inhibitory effects were dose-dependent and were enhauced when the cultures contained the carboxy-O-methyl transferase inhibitor, U-0521. The
doi:10.1016/0014-5793(90)81441-p
pmid:2262003
fatcat:2cfnb6norzbkvlnjq5m5cv3lma