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Macrophages cultured from the peripheral blood of normal individuals, tuberculoid leprosy patients and long-term-treated, bacteriologically negative lepromatous leprosy patients are able to release hydrogen peroxide on stimulation with Mycobacterium leprae. Macrophages from lepromatous leprosy patients who are bacteriologically positive produce considerably lower levels of hydrogen peroxide, even though stimulation of these cells with Mycobacterium leprae is definitely demonstrable. Thisdoi:10.1007/bf02712154 fatcat:ziqzbsbkybcnjotcsvohnd2da4