Imaging the carotid atherosclerotic plaque

Sandra Neumann, Elena Giulia Milano, Chiara Bucciarelli-Ducci, Giovanni Biglino
2019 Vascular Biology  
This mini review provides a concise overview of imaging techniques that are currently use to image the atheroscletoric plaque in the carotid artery in vivo. The main techniques include ultrasound imaging, X-ray imaging, magnetic resonance imaging and positron emission tomography imaging. Each technique has advantages and limitations and may be chosen depending on the availability, cost and clinical justification for its use. Common to all the imaging techniques presented here is the need for a
more » ... killed imaging professional to allow for high reliability and repeatability. Whilst ultrasound-based imaging currently is regarded as a first line technique in clinical practice, the use of other techniques such as computed tomography angiography (CTA) or magnetic resonance angiography (MRA) needs to be considered in presence of significant stenosis with or without symptoms. Advancements in these two modalities, as well as in PET imaging, are increasingly moving toward a better understanding of the risk-stratification and pre-interventional monitoring of patients at risk of plaque rupture as well as early identification of plaque development and better understanding of plaque composition (e.g. metabolic imaging).
doi:10.1530/vb-19-0010 pmid:32923954 pmcid:PMC7439847 fatcat:uuppzfa3zbf6fdtzmxnnetje7q